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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96854d514cea763576d2d64f40705c8de4a307001b33bce2b0965394715486a2' 
  AND token = 'JYbFh+oZnJeeChOjktwEQmKlK6V8ldWPibWcdIm4Sls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}