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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ee97ae0be74deef1a5bd2ac9df019d99c34462f2a1bec9f245af6f45bd849d' 
  AND token = 'KhW7RD+Y00I+rI0TnCSAshMNirdo7JeqLq4dHRz0WcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}