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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49d5706c368494b0d49308ffa1c05d00e43bbe247eb48408138c35a8ed9e859' 
  AND token = '5yvbHlnaaHyrqvFDSm/pmlIsRNMSWRFY1z3ILpG2bTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}