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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7a6253fb8d95b917ab6473dc3dbe6d4da8c5272c7d58dff6979447db277677' 
  AND token = 'I7TQ/HbnwS6Rf44Dsg9+Y+L8G26mu0e9LL55HHyAjUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}