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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdcf214bbcebde7b2b05107fba4d620c3024a0343706be78b78582a81de1cce' 
  AND token = 'A/yIIbM71d0Oq+/oKi7e06XWPPnGYBj/PQ1hHgjMbxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}