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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e068e2ca65a4c991a3c89383f9d43f32258efad0d575610a63ef9ed17c6010' 
  AND token = 'u4m1pAcqvXeR8gcsWbHA7fmhAmn0LFAlZoWJdy0M+C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}