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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b5af5f232fabcd5365090336681f9edf219ece66e7f5a9d71a6ac80028cec5' 
  AND token = '2wh0avNiLUO1WAwMDKdoJE00xb111d4I9dGTY495WkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}