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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272c7e4e1a1e4b90c408f4d23ce581bd7369fec777439e4b3d73b741be7c95cf' 
  AND token = '5hekiahZIIF1dzVYX5KAWFI3soRdM4oJQTmhXGPlThQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}