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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ef10c9c7c8504c075978254eeb1662c25b11a98a9c2835380d14d5a96e06f0' 
  AND token = 'sxXc6ock5oUQVXJm12XF5SfVj8Z92iGsVlQzbfGSX8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}