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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8c64d20e836c5c1883840641f69b7350d7750957aec0530b7eee1ec8e38789' 
  AND token = 'OyYzsMcV7UGm6uxBN9KdxBCyqKESYrFm+ign6NmwWs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}