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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aae17ec648d06f6aa1b255f14bceb5c248e0dec142c7e8488e60d64a7aec1000' 
  AND token = 'k3mU8RE85i+6U+c1+8Cs7n+Hc3vTV7JEDgcCjGNxNiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}