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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b379cb35bdf85bc07bfa24e8e017d9538ce52470d0a9d15198ccae5889fce610' 
  AND token = '6NTaix2VW2OnN5ae206rQUcCTra24ifIpFutZczUyM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}