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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6172af36dda2401a3778c34d617b9ca345f2e9c7d94e6997a6b86614c38ab218' 
  AND token = 'k49/PZxKCWlpAbWeDzfSk4hXBstdsTv56H4Dj9VH5uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}