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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e43e6dd9354c87463f38b2c86c89d65140e1c9144452ac46bf60949b1d2bb8' 
  AND token = 'jzE46k48W7SJ3LYQVl6FPEgVR5WABe+1YRkJ5BRUEzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}