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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15bcbf90b3951e945bf9269c6db635e446b128e8b5674b6c49b6e0ef1ec8b89b' 
  AND token = 'CXww4pR3tessxSAvid/M6s3PBOQxYpXRTW4FrGQWF24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}