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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73718a33eec003a92141a5f57e3b2f0c18f4d674400fce7d6586fd6420a0aa8e' 
  AND token = 'KrtfXOzD79jfRYYGOdA4mEaL4ioNpilXEPWTyBKyUoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}