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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06453a9c787fce77e750fc6ea3eab68c06af85319b580c1dbe8e56c715122081' 
  AND token = 'N0bULqIEGZCbet1AIWjpJ69H7iTZoKLjdWQLMHAXKMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}