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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73836a217d846428e03dc572cba344ae0e4a3d25c0b0331564684a9fcc651f9a' 
  AND token = 'GIg4uJj+TazzlvEvFuREy5v+qer6SqnMFO22eTL9YmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}