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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1322e74bdbd860627d19296a27fafd252dd2180850df74aee0226a9ad87e64b1' 
  AND token = '7d/GGL7gr5xa+YR3qtL6FayTGkvukbFfC2KO3ILNllo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}