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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfea48ee945e8d2d2741c422978ce44d1076572c34b20ede69ee80c9a615a22' 
  AND token = 'HbdEQ632at8qpDhwc/dnIsbn1DxO6PEatnn5w3yCq80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}