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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0144f2d31e29a8ff2b13c666d7ac3515e529e1c26b9ae50d259e3f13524c435' 
  AND token = 'XPQ19M/moy44LoxZ5eNI1XxSWlVgFlq6AsoVCQdck5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}