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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265b8ef072f36143d54407a05fbface6cc2ff7c1a4f215b7e555756d489097b9' 
  AND token = 'rxYoN4fcAsrpO3AGmYOxKo65VlhWtYpEbDI1PXkSmks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}