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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50901fbd41b3844bd2c5ddbbc820c1f3898be2474eecae6c4db59d2664f015fb' 
  AND token = 'uvjt5//xv5EwTCk7t4B2z8ijyBV3CfpW/SCp1M4ZQoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}