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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa14227abd4e3283c7a289ba3fb1318376373dece73a5e43565b90f781379084' 
  AND token = 'afDqns4syhg9KtUE81jdk1+idNrOh7jX4uAAdi9MwLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}