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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6a5d98efaab14240d23cc9b421588516e9e1f6c62e2cb76e2d37c063c0888e' 
  AND token = '5t0X/YdXuxdYlqQjS9A41vuH68R0oxyTeFYhXb/hMdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}