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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146ad4ff2db57a852cb68e7d77b9ecdef10c627e0a0dda6f08d9ee07793939ee' 
  AND token = '2TXsABPvj2/De1pyXzQBnytTo42PdlmWcQAUqjdjGwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}