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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337c8bdba22c1acbf702481a2af66b8e0250d0b2e7ca073f448059028a1bf81b' 
  AND token = 'w58x8v0/VAoNSTb7Fo78WG8x4sYwjbm53vE4ILtiY1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}