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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab37d89a0509977cb6342255652f13215f3cc0a6117d114e8deba9c1fd2e3a6' 
  AND token = 'I8dq6L+kbnf8Xe9OyLnn0Ba2fqzC5jZDDz8BKMylk58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}