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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aaa1db23b04b45581837d4450a9283d86aa857f8ec64000ff4716f14a218b7b' 
  AND token = 'FCXiwDU8U0D/ZKEdxEqg1dzQwEr3C7pbDY6DwV9jy08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}