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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7761185b75230cf97194b0887ece53805caa4700088a4c87b1378b7cb9b44cbe' 
  AND token = 'vGgp+W+MKrRQCaRfhu3OFhEZDPplE1tjSoR3URO+yYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}