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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3649c7c9efc99feec88f22581eb1218ee16b9325613fba4664a43b75e1a745' 
  AND token = 'N6WrnP4D/+So3ovV4r3nIVo0vIcrfxonl6TKkeNsUII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}