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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25f494343908d82b52e2f0c304ba8a400cb2e7b164b49a87fc04cefcca4c318' 
  AND token = '+ZMvcW0UW0KXutk7tfmCXxb5DZvdKl4n+YMGnxu88P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}