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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654d1817debdef8fa9216f43c5cdfdf4e93b4bd6e7cee2859264c7b2282e7630' 
  AND token = 'lT398NDlSRxQvTSAazbCSwDMq12QRM2rm3R1KA2ho+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}