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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580e151290392564c8421767ce214b46126933491d17cc8619829e3b9c6b6e39' 
  AND token = '+2LI37UyNIUjlTCFISRzqe6Gl+EBqHbsM2aedh1EVVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}