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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8182225bf289c02d068a5185836191831db16b67b146ae5fd0af3f8a54e8d3' 
  AND token = '72MESV6HkXzq79IkBkw37s7CMaMT5ZENVCPnmhLrFK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}