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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43017670f4a892d668d237a5357852c19274d6b7c2084e1352c08435a517ec65' 
  AND token = 'FkHmRbEMKATyB4OlHDQnOPRo1Sh43RNs+tWyZO92wMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}