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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'faf95295423e703d5ec3d54826908bc33edee48ed4020e3a3824e8b9b76ca8e5' 
  AND token = 'AlAY39vTQbdmIPseuTsMiQ+mY3RwA3JSd4q4Vz23NuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}