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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f47947a8bc8eda71fa90305d5a5451e5c36e2925d1c97ef4f9f59f37ad2db1a4' 
  AND token = 'HECdhdTH3/+T7mrHKJhOYJDiEl8GyEafpDOyhnLQ4mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}