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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d0f57d2597bbc671eda591304f18e4b4f2945a90a27c04d564a30f48cbe14b' 
  AND token = 'Uv6zZLZQfhm2vssY1XG+OAqLsksGNB7NasVH981kCO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}