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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef24aa5b86b71421259c3c87c13c1d9d8e236d1afc1cd380386c2d9192ee0819' 
  AND token = '/TZElG/KbZwv1xRf2VDLFHAlhKahWn35caAbTQ1CIlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}