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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2082591d2e857fd9a89be69d34502e25a0ad9dc87febc0b4b980b4d7dc1f10' 
  AND token = 'bwwqs8z2t4z/iu2SXzlX+iMMG0erdqO7SIwlSkq3wuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}