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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79495ba1bc2e023b2beb53e3a3a9e6d83fb7727f639ddbe2dabaec357fcf3c73' 
  AND token = 'QPVb5+hhvEUrKGJerVRzDmrO/Ipt4FFEjLnHQdvBijk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}