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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e509ea4f87e4899e30e29c6952f21c6b391745495a5addd6834e5a0e77bf4480' 
  AND token = '2ycON04Yf5QgosdUgpLkfnRvpYYwTGxeeLPP5O4tnas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}