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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33ec49950fc43bee2bb4d9f1d7a13e844e31d36b7a8086401bbf76125b51770' 
  AND token = 'Iv1PkQ2XFsDcX/jDS1gRWBW43RtDa98rcTXZ5hISt8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}