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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43316a9111d85751e1e46cbad965514fcc5bb7ed95ba3fc3c8c01033fc50981c' 
  AND token = 'pwHa0SeJ2nsOi1cL0Cf2Ph2yQP+9fHvb/EbDaoCw85A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}