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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18274cd8118c81f08160fcfddd169bc1ca5b32d45c287bd2ec2220be824c9aff' 
  AND token = 'EYTR2M0r2xj2vcyjum0ll1d5k4ZLVxPILzrU5c0nCBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}