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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6eff971edf5019e9107ee02a574f35f17fc3ffc785c3b0673394a1eba2f411' 
  AND token = 'uP0muHEOHlKMEyZo3G8OUsz3FGTD6vwiBknp9LgQKLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}