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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2333ae5c41ac3fa72f761444a9a3a2311527f6fac77a9e7c05eab98b661b53c2' 
  AND token = 'EMFrTmD7X/4UXaKJES2JcmRvLhci1t+2rqPOvJHgNmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}