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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48ecca5a3be520092612d00395227fe5f8d3d0b7021a947e94d551b4068fdbe' 
  AND token = '6a91A2ru4rADbnc3LTV0bbzxroEcVJGyeQJVF6XZCLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}