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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acbcb96e5f459e67abc562a672142e17abfbbc34e39aaae14a716cae9b250ad' 
  AND token = 'mME8WYbPpo3LvS0VdC6sGDFTp0HuAafhkQZtLwlsxv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}